Aditya Choudhary et al. Froin Syndrome. 1Aditya Choudhary, 2Manoj K Goyal, 3Manish Modi, 4Kanchan K Mukherjee, 5Chirag K Ahuja, 6Vivek Lal. Georges Froin (–), a French physician practising at the turn of the century, was the first to describe the xanthochromia and marked coagulation of. Froin Syndrome is characterized with xanthochromic CSF, high CSF protein content, complete blockage of CSF circulation. We reported our case of Froin.

Author: Arakazahn Tukora
Country: Japan
Language: English (Spanish)
Genre: Art
Published (Last): 28 May 2010
Pages: 135
PDF File Size: 3.79 Mb
ePub File Size: 12.18 Mb
ISBN: 819-6-94947-646-5
Downloads: 47364
Price: Free* [*Free Regsitration Required]
Uploader: Mikakree

It is caused by meningeal irritation e.

Pseudo-Froin’s syndrome, xanthochromia with high protein level of cerebrospinal fluid

This condition may also be seen in meningitidis and epidural abscesses. The patient’s CSF showed froln protein 3, Indian J Med Sci. Find articles by Soon-Kul Kwon. Gazette des hopitaux, Paris; The patient was referred to neurosurgery clinic after he and his relatives had been informed. InMax Nonne explained spinal cord blockage related with high protein content.

The CSF studies were performed within 30 min after collection of the fluid.

High protein content of CSF has many reasons. Orphaned articles from January All orphaned articles Infobox medical condition new All stub articles. Spectrophotometric analysis of xanthochromia is recommended for distinction between a traumatic spinal tap and a true intracranial bleed in cases when a yellow color of the CSF is observed.

Nonne-Froin sign | QJM: An International Journal of Medicine | Oxford Academic

His paper was published in Gazette des hopitaux in [ 1 ]. From Wikipedia, the free encyclopedia. It furthers the University’s objective of excellence in research, scholarship, and education by syndroje worldwide.


Cranial and spinal cervical, thoracal and lumbar MRI revealed an intramedullary mass lesion 63 x 13 mm in size at level of T2-L1 spines T1 hypointense, T2 peripherally hyperintense. Adams RD, Victor M editors. Select your language of interest to view the total content in your interested language.

Guidelines on routine cerebrospinal fluid analysis. No motor or sensory abnormalities were found in the upper chest or upper extremities.

Pseudo-Froin’s syndrome, xanthochromia with high protein level of cerebrospinal fluid

Cerebrospinal fluid CSF was seen to be xanthochromic clear light yellow, citrine. Causes of a dry tap are blocked needle, needle in the wrong space, spinal surgery, and low CSF pressure. Spinal drug administration was done after CSF confirmation by aspiration. The patient underwent head CT that showed two hypodense lesions in the right cerebellum and right fronto-parietal lobe with slight central enhancement, consistent with brain metastasis, these lesions did not explain his neurological findings.

In the case discussed here, the patient had suffered from year paraplegia with newly-developed urinary bladder cancer and showed abnormal CSF characteristics at spinal anesthesia. Find articles by Mi-Woon Kim.

Email alerts New issue alert. Comparative values of CSF-cholesterol and CSF-triglycerides along with other biochemical parameters in neurological disorders.

CSF cytologic examination was negative for malignant cells. Microbiology results were normal.

Incidental Finding of Froin Syndrome during Spinal Anesthesia in a 72-Year-Old Patient

Support Synrrome Support Center. Agri and Aquaculture Journals Dr. CSF is xanthochromic in spinal block, subarachnoidal hemorrhage SAHGuillian-Barre Syndrome, subdural hematoma, tumors acustic neurinomaacute purulent menigitidis, blood dyscrasias [ 2 ].

  EB 1775W PDF

Close mobile search navigation Article navigation. In Froin’s syndrome, blockage of the spinal canal and stagnation of the CSF develops due to an obstructing inflammatory or neoplastic lesion.

Can’t read the image? Similar to Miraz’s case of Pseudo-Froin’s syndrome, with a large bulging disc in the lumbar spine, this case showed xanthochromia, high protein content, marked coagulation of the CSF, and dry tapping without spinal meningitis, malignancy, or abscess. Please introduce links to this page from related articles ; try the Find link tool for suggestions. Patient was put into sitting position.

His past medical history was remarkable for diabetes mellitus, hypertension and heavy smoking. We obtained cranial and spinal MRI in order to support the diagnosis. Dry tap and spinal anesthesia. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License http: No specific problems such as headache, reflex tachycardia, or sweating were observed in the perioperative period. The patient had suffered from paraplegia for 20 years because of a thoracic spine burst fracture T and dislocation.

Guillian-Barre syndrome GBS was considered as the most likely diagnosis and the patient was referred to lumbar puncture and further workup.